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Results in impaired collagen synthesis, causing capillary fragility, poor wound healing, and bony abnormalities. Known clinically as scurvy. |
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Most common in children 6-12 months of age who are fed a diet deficient in citrus fruits and vegetables. |
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Clinical manifestations: Malaise, anorexia, limb tenderness and swelling, costochondritic enlargement, easy bruisability, and petechiae. |
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Oral manifestations: Gingival swelling and discoloration with petechial hemorrhages on the mucous membranes, loosening of the teeth, and early tooth loss. |
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Vitamin D deficiency presents as Rickets with the bony manifestations of craniotabes, rachitic rosary, delayed fontanelle closure, and long bone deformities. |
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Dental manifestations can also occur, including delayed eruption,
Intensely hard calcareous substance that forms a thin layer partly covering the teeth; the hardest substance of the animal body; consists of minute prisms arranged at right angles to the surface and bound together by a cement substance.
enamel defects, and enamel caries. |
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Several factors in the clotting cascade are Vitamin K dependent, so deficiency results in excess bleeding and easy bruisability. |
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May manifest as bleeding of the gums, especially with brushing. |
