Patients with indwelling lines or certain types of cardiac disease require antibiotic prophylaxis for some dental and surgical procedures.
For Subacute Bacterial Endocarditis prevention, standard prophylaxis is Amoxicillin 50 mg/kg by mouth 1 hour prior to the dental procedure. For penicillin-allergic patients, this should be substituted with Clindamycin, a cephalosporin, or a macrolide (eg, Azithromycin).
For additional information regarding cardiac lesions requiring therapy and antimicrobial options, please refer to the Red Book®, available from the American Academy of Pediatrics.
