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Dental Antibiotic Prophylaxis
Patients with indwelling lines or certain types of cardiac disease require antibiotic prophylaxis for some dental and surgical procedures.

For Subacute Bacterial Endocarditis prevention, standard prophylaxis is Amoxicillin 50 mg/kg by mouth 1 hour prior to the dental procedure. For penicillin-allergic patients, this should be substituted with Clindamycin, a cephalosporin, or a macrolide (eg, Azithromycin).

For additional information regarding cardiac lesions requiring therapy and antimicrobial options, please refer to the Red Book®, available from the American Academy of Pediatrics.

First-line therapy for Subacute Bacterial Endocarditis is Amoxicillin.
Options for Penicillin-allergic patients include Clindamycin, cephalosporins, and macrolides.
The American Heart Association has recently revised the guidelines for cardiac lesions requiring prophylaxis.

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